1Department of Veterinary Medicine, College of Agriculture and Veterinary Medicine,
Qassim University, P.O. Box 6622, Buraidah, 51452, Saudi Arabia
2Department of Animal Medicine, Faculty of Veterinary Medicine, Zagazig University, Zagazig, Egypt
This study was designed to investigate the effect of 8 km training on the serum concentrations of the cardiac biomarkers troponin I (cTnI) and creatine kinase myocardial band (CK-MB) in 23 healthy racing camels (Camelus dromedarius). From each camel, 2 blood samples were collected; before training (T0) and within 2 h after training (T1). Serum concentrations of cTnI and CK-MB, and hematobiochemical profiles were estimated. Compared to a value of 7.21±1.9 ×109/L pre-training, neutrophils decreased significantly to 6.2±2.2 × 109/L post-training (P=0.05). Similarly, haemoglobin concentration decreased from 11.1±1.1 g/dL before training to 10.3±2.0 g/dL after training (P=0.0002). The MCV showed a similar pattern where it decreased from 26.0±1.3 (fl) pre-training to 24.0±3.6 (fl) post-training (P=0.01). Other haematological variables did not show any significant changes before and after training (P>0.05). The serum activity of AST increased from 85.5±12.8 U/L before training to 91.5±8.6 U/L after training (P=0.0001). Serum concentration of TP increased also from 54.2±8.7 g/L pre-training to 59.0±3.8 g/L post-training (P=0.04). On the contrary, the serum concentration of lactic acid decreased from 3.9±0.8 (mmol/L) before training to 3.3±0.4 (mmol/L) after training (P=0.004). Other biochemical variables did not show any significant changes before and after training (P>0.05). Before training the serum concentration of cTnI was 0.03±0.03 ng/mL; a value that did not differ significantly when compared to the value of 0.04±0.02 (ng/mL) after training (P=0.60). The CK-MB value differed significantly before and after training (0.47±0.1 ng/mL before training vs 0.48±0.8 ng/mL after training; P=0.004). In conclusion, the cardiac biomarker cTnI did not change significantly after training compared to baseline levels, a result that disagrees with values in camels after race. However, the CK-MB increased significantly after training compared to pre-training serum concentrations.
Key words: Cardiac biomarkers, cTnI, CK-MB, racing camels, training