Camels and Camelids

EFFECT OF ENROFLOXACIN ON HEPATIC MICROSOMAL MIXED FUNCTION OXIDASES IN CAMEL

Journal Edition: December 2014
Article DOI: 10.5958/2277-8934.2014.00029.0
Published On: 03-09-2018 19:07

Mohammed H. Al-Nazawi
Department of Physiology, Biochemistry and Pharmacology, College of Veterinary Medicine and Animal Resources,
King Faisal University, PO Box 400, Al-Ahsa 31982, Saudi Arabia

ABSTRACT

Administration of enrofloxacin at a dose of 5 mg/kg intramuscularly for 3 days has resulted in a significant decrease in aminopyrine-N-demathylase and aniline-4-hydroxylase in liver of camel compared to saline treated (controls). It is suggested that co-administration of drugs metabolised by phase-I reaction with enrofloxacin should be avoided in camels.
Key words: Camel, enrofloxacin, hepatic, oxidases