Mohammed H. Al-Nazawi
Department of Physiology, Biochemistry and Pharmacology, College of Veterinary Medicine and Animal Resources,
King Faisal University, PO Box 400, Al-Ahsa 31982, Saudi Arabia
ABSTRACT
Administration of enrofloxacin at a dose of 5 mg/kg intramuscularly for 3 days has resulted in a significant decrease in aminopyrine-N-demathylase and aniline-4-hydroxylase in liver of camel compared to saline treated (controls). It is suggested that co-administration of drugs metabolised by phase-I reaction with enrofloxacin should be avoided in camels.
Key words: Camel, enrofloxacin, hepatic, oxidases