EFFICACY OF HERD-SPECIFIC AUTOGENOUS VACCINE AGAINST CONTAGIOUS LYMPHADENITIS IN DROMEDARIES - PRELIMINARY REPORT
Journal Year: 2012
Journal Month: December
Published On: 03-09-2018 19:11:00
Article DOI:

U. Wernery, M. Joseph, R. Thomas, R. Raghavan, G. Syriac and A. Varghese
Central Veterinary Research Laboratory, P.O.Box. 597, Dubai, UAE

ABSTRACT

In a first experiment of this kind in dromedaries, the efficacy of a herd specific autogenous vaccine containing a formalin inactivated C. pseudotuberculosis culture supernatant was assessed in Kenya. This vaccine which contained 300μg/ml PLD was subcutaneously injected thrice at the neck of 117 dromedaries of which 26 were calves between 4 to 6 months. All dromedaries suffered from generalised CLA with abscess formation mainly in front of the shoulder. All dromedaries possessed antibodies to CLA. After 2 vaccinations, no more abscesses developed and existing abscesses receded in adult dromedaries whereas a similar success was observed in young calves after the 3rd vaccination when their age had reached 12 months. It is believed that herd-specific strains and the amount of PLD in the vaccine are important factors for the efficacy.
Key words: Caseous lymphadenitis, dromedaries, vaccine


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