Camels and Camelids

EXPLORATION OF INTESTINAL ABSORPTION AND RENAL EXCRETION OF CALCIUM BY STABLE STRONTIUM TEST IN CAMELS (Camelus dromedarius)

Journal Edition: December 2003
Article DOI:
Published On: 13-12-2018 06:54

M. El-Khasmi, F. Riad1, A. Safwate2, M. Farh3, A. Belhouari4, K. Hidane5,N. El Abbadi6, B. Faye7 and V. Coxam8
Department of Biology, Faculty of Sciences, Ben M’sik-Sidi Othman, BP 7955, Casablanca, Morocco
1-4Unité de recherche: Hormones et Métabolisme. Département de Biologie,
Faculté des Sciences Ben M’Sik-Sidi Othman. Casablanca, MOROCCO
5DPA, Service Vétérinaire, Dakhla. Sahara , Maroc
6Laboratoire des applications Médicales et Biologiques, Centre National de l’Energie des
Sciences et des Techniques Nucléaires. Rabat, Maroc
7CIRAD- EMVT, Montpellier, France
8INRA de Theix, 63122 Saint-Genès Champanelle, Clermont-Ferrand, France

ABSTRACT

The present study was undertaken to evaluate the intestinal calcium absorption using stable strontium (Sr) as a surrogate marker in five newborn camels. Two tests were performed with an interval of 10 days for calculating the within-animals variation of plasma Sr (CV%). The area under the concentration-time curve (AUC0-300) 5 hours after an oral SrCl2 load of 4.1 mmol was 10.11 ± 0.542 mmol/L-1/min. The within-animals CV% of AUC0-300 was 11.6. In our animals, plasma calcium (Ca) and phosphorus (Pi) levels were not significantly modified by Sr load. The fractional Sr excretion 5 hours after oral load in percentage of Sr dose administered was 1.03 ± 0.22% and Sr renal clearance was 4.12 ± 0.51 mL/min. Sr test had no significant effect upon renal excretion of Ca and Pi. Our results showed that in newborn camels, Sr absorption test is simple, reproductible and may be used in exploration of intestinal Ca absorption.
Key words: Calcium intestinal absorption, dromedary, strontium test