Sakar Palecha, TK Gahlot and Praveen Bishnoi
Department of Veterinary Surgery and Radiology, College of Veterinary and
Animal Science, Rajasthan University of Veterinary and Animal Sciences, Bikaner 334001, India
ABSTRACT
The study was designed to evaluate the suitability of midazolam as sedative in dromedary camels. Midazolam was administered at a dose 0.4 mg kg-1 body weight, intravenously as a bolus in 6 camels for induction of sedation and determination of sedative effects on the behaviour and various physiological, haematological and biochemical parameters of camels were evaluated. Midazolam produced sedation of short duration (5-7 min) with mild to moderate depression of palpebral and corneal reflexes, moderate salivation and lacrimation, mild to moderate relaxation of jaw, tail, limbs, abdomen and anus. Rectal temperature and pulse rate showed non-significant increasing trend whereas, significant increase in respiration rate was observed at 5 and 10 min 12.83±0.83 and 12.66±0.42, respectively while significant decrease in respiration rate at 40 min 10.0±0.5 were observed, compared with base line value of 11.0 ± 0.36. No appreciable changes in haematological parameters and the activity of ALP, ALT, AST and LDH enzymes were observed in the present study. Intravenous administration of midazolam proved safe sedative agent when used alone for chemical restraint for a variety of diagnostic and minor surgical procedures of short duration in camels.
Key words: Camel, dromedary, midazolam, sedation
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